Role of Bcl-2 family members in immunity and disease

Nathalie M. Droin; Douglas R. Green

doi:10.1016/j.bbamcr.2003.10.011

Role of Bcl-2 family members in immunity and disease

Nathalie M. Droin, Douglas R. Green

Résultats de recherche: Contribution à un journal › Article 'review' › Revue par des pairs

62 Citations (Scopus)

Résumé

The different members of the Bcl-2 family are essential regulators of programmed cell death. These different members share one or more Bcl-2 homology domains, required for their ability to regulate each other. In this review, we describe current knowledge of the functions of different Bcl-2 members and their potential roles in disease and immunity.

langue originale	Anglais
Pages (de - à)	179-188
Nombre de pages	10
journal	Biochimica et Biophysica Acta - Molecular Cell Research
Volume	1644
Numéro de publication	2-3
Les DOIs	https://doi.org/10.1016/j.bbamcr.2003.10.011
état	Publié - 1 mars 2004
Modification externe	Oui

Accès au document

10.1016/j.bbamcr.2003.10.011

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Contient cette citation

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title = "Role of Bcl-2 family members in immunity and disease",

abstract = "The different members of the Bcl-2 family are essential regulators of programmed cell death. These different members share one or more Bcl-2 homology domains, required for their ability to regulate each other. In this review, we describe current knowledge of the functions of different Bcl-2 members and their potential roles in disease and immunity.",

keywords = "Apoptosis, BH3-only protein, Bcl-2, Disease, Immunity, Regulation",

author = "Droin, {Nathalie M.} and Green, {Douglas R.}",

year = "2004",

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T1 - Role of Bcl-2 family members in immunity and disease

AU - Droin, Nathalie M.

AU - Green, Douglas R.

PY - 2004/3/1

Y1 - 2004/3/1

N2 - The different members of the Bcl-2 family are essential regulators of programmed cell death. These different members share one or more Bcl-2 homology domains, required for their ability to regulate each other. In this review, we describe current knowledge of the functions of different Bcl-2 members and their potential roles in disease and immunity.

AB - The different members of the Bcl-2 family are essential regulators of programmed cell death. These different members share one or more Bcl-2 homology domains, required for their ability to regulate each other. In this review, we describe current knowledge of the functions of different Bcl-2 members and their potential roles in disease and immunity.

KW - Apoptosis

KW - BH3-only protein

KW - Bcl-2

KW - Disease

KW - Immunity

KW - Regulation

UR - http://www.scopus.com/inward/record.url?scp=1442310923&partnerID=8YFLogxK

U2 - 10.1016/j.bbamcr.2003.10.011

DO - 10.1016/j.bbamcr.2003.10.011

M3 - Review article

C2 - 14996502

AN - SCOPUS:1442310923

SN - 0167-4889

VL - 1644

SP - 179

EP - 188

JO - Biochimica et Biophysica Acta - Molecular Cell Research

JF - Biochimica et Biophysica Acta - Molecular Cell Research

IS - 2-3

ER -