TY - JOUR
T1 - Sentinel node and breast cancer
T2 - A state-of-the-art in 2019
AU - Zeitoun, J.
AU - Babin, G.
AU - Lebrun, J. F.
N1 - Publisher Copyright:
© 2019 Elsevier Masson SAS
PY - 2019/6/1
Y1 - 2019/6/1
N2 - Since 1994 and Giuliano's description of sentinel lymph node technique, this procedure has considerably improved and is nowadays, one of the essential pillars in the management of breast cancer. Neoadjuvant chemotherapy (NAC) is effective on regional control, especially on axillary lymph node. Various learned societies recommend that the initial proved GS can be realized before (CNGOF 2010, Saint-Paul de Vence 2013, ESMO 2015, St-Gallen 2015, NCCN 2016) or after (ASCO 2014, ESMO 2015, Saint-Gallen 2015) CNA when the patient is considered like N0. In patients with initial lymph node involvement, GS searching it is not yet recommended. SLN detection before NAC remains an important prognostic factor especially in N+ patients before surgery. The purpose of this article was a reviewing of medical literature regarding possible indications for SLN detection and axillary dissection in patients with NAC according to sentinel lymph node status. The secondary objective was to put forward different perspectives and studies dealing with this subject. The complete pathological response appears to be an important selection criterion for proposing SLN to these patients and avoiding a “useless” AD. It is important to include patients in the trials to make recommendations progress on SLN after NAC and avoid a rate of uninjured AD.
AB - Since 1994 and Giuliano's description of sentinel lymph node technique, this procedure has considerably improved and is nowadays, one of the essential pillars in the management of breast cancer. Neoadjuvant chemotherapy (NAC) is effective on regional control, especially on axillary lymph node. Various learned societies recommend that the initial proved GS can be realized before (CNGOF 2010, Saint-Paul de Vence 2013, ESMO 2015, St-Gallen 2015, NCCN 2016) or after (ASCO 2014, ESMO 2015, Saint-Gallen 2015) CNA when the patient is considered like N0. In patients with initial lymph node involvement, GS searching it is not yet recommended. SLN detection before NAC remains an important prognostic factor especially in N+ patients before surgery. The purpose of this article was a reviewing of medical literature regarding possible indications for SLN detection and axillary dissection in patients with NAC according to sentinel lymph node status. The secondary objective was to put forward different perspectives and studies dealing with this subject. The complete pathological response appears to be an important selection criterion for proposing SLN to these patients and avoiding a “useless” AD. It is important to include patients in the trials to make recommendations progress on SLN after NAC and avoid a rate of uninjured AD.
KW - Adjuvant chemotherapy
KW - Axillary dissection
KW - Breast cancer
KW - Sentinel ganglion
KW - Sentinel lymph node detection
UR - http://www.scopus.com/inward/record.url?scp=85065516300&partnerID=8YFLogxK
U2 - 10.1016/j.gofs.2019.04.002
DO - 10.1016/j.gofs.2019.04.002
M3 - Short survey
C2 - 30959186
AN - SCOPUS:85065516300
SN - 2468-7197
VL - 47
SP - 522
EP - 526
JO - Gynecologie Obstetrique Fertilite et Senologie
JF - Gynecologie Obstetrique Fertilite et Senologie
IS - 6
ER -