Shigella Targets the Mitochondrial Checkpoint of Programmed Necrosis

Lorenzo Galluzzi; Guido Kroemer

doi:10.1016/j.chom.2009.01.002

Shigella Targets the Mitochondrial Checkpoint of Programmed Necrosis

Lorenzo Galluzzi, Guido Kroemer

Résultats de recherche: Contribution à un journal › Brève enquête › Revue par des pairs

22 Citations (Scopus)

Résumé

In nonmyeloid cells, Shigella hijacks the mitochondrial checkpoint of cell death, thereby inducing a regulated form of necrosis depending on Bnip3 and cyclophilin D. Carneiro et al. (2009) describe the interplay between this program and a prosurvival response transmitted via the Nod1/Rip2/NF-κB/Bcl-2 axis, which determines the fate of infected cells.

langue originale	Anglais
Pages (de - à)	107-109
Nombre de pages	3
journal	Cell Host and Microbe
Volume	5
Numéro de publication	2
Les DOIs	https://doi.org/10.1016/j.chom.2009.01.002
état	Publié - 19 févr. 2009

Accès au document

10.1016/j.chom.2009.01.002

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abstract = "In nonmyeloid cells, Shigella hijacks the mitochondrial checkpoint of cell death, thereby inducing a regulated form of necrosis depending on Bnip3 and cyclophilin D. Carneiro et al. (2009) describe the interplay between this program and a prosurvival response transmitted via the Nod1/Rip2/NF-κB/Bcl-2 axis, which determines the fate of infected cells.",

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