Soft tissue sarcomas in HIV-infected adult patients

K. Fizazi, J. Feuillard, A. Le Cesne, P. Terrier, M. Raphael, P. Pouillart, T. Tursz

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    Résumé

    Clinical and biological features of three HIV-infected adults with soft tissue sarcoma are reported. Epstein-Barr Virus (EBV) detection was negative using in situ hybridisation, PCR analysis and Southern blot analysis in the two cases for which tumour samples were available, contrary to all previously reported paediatric cases. All three patients developed métastases. Chemotherapy was feasible but only afforded tumour stabilisation. The cause of death in all three cases was distant spread and not AIDS. Soft tissue sarcomas associated with HIV infection are not exclusively found in children, do not appear to be EBV-related in adult patients, and fare dismally despite vigorous therapy.

    langue originaleAnglais
    Pages (de - à)1809-1811
    Nombre de pages3
    journalEuropean Journal of Cancer
    Volume32
    Numéro de publication10
    étatPublié - 1 déc. 1996

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