Specificities of clinical research in radiotherapy

C. Hennequin; D. Azria; P. Blanchard; G. Créhange; Deutsch; A. Lisbona; Moyal; D. Pasquier; L. Roca; S. Supiot; P. Giraud

doi:10.1016/j.canrad.2021.11.011

Specificities of clinical research in radiotherapy

Titre traduit de la contribution: Spécificités de la recherche clinique en radiothérapie

C. Hennequin, D. Azria, P. Blanchard, G. Créhange, Deutsch, A. Lisbona, Moyal, D. Pasquier, L. Roca, S. Supiot, P. Giraud

Résultats de recherche: Contribution à un journal › Article › Revue par des pairs

3 Citations (Scopus)

Résumé

The aim of this review is to present the specificities of clinical research in radiation oncology. Objectives are similar to all research in oncology: to improve the efficacy and to decrease toxic effects. Phase III trials remain the main methodology to demonstrate an improvement in efficiency, but phase I-II and registers are also important tools to validate an improvement in the therapeutic index with new technologies. In this article we discuss the special features of end-points, selection of population, and design for radiation oncology clinical trials. Quality control of delivered treatments is an important component of these protocols. Financial issues are also discussed, in the particular context of France.

Titre traduit de la contribution	Spécificités de la recherche clinique en radiothérapie
langue originale	Anglais
Pages (de - à)	104-107
Nombre de pages	4
journal	Cancer/Radiotherapie
Volume	26
Numéro de publication	1-2
Les DOIs	https://doi.org/10.1016/j.canrad.2021.11.011
état	Publié - 1 févr. 2022

Accès au document

10.1016/j.canrad.2021.11.011

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