Spermidine reduces cancer-related mortality in humans

Federico Pietrocola; Francesca Castoldi; Oliver Kepp; Didac Carmona-Gutierrez; Frank Madeo; Guido Kroemer

doi:10.1080/15548627.2018.1539592

Spermidine reduces cancer-related mortality in humans

Federico Pietrocola, Francesca Castoldi, Oliver Kepp, Didac Carmona-Gutierrez, Frank Madeo, Guido Kroemer

Résultats de recherche: Contribution à un journal › !!Comment/debate

30 Citations (Scopus)

Résumé

A recent prospective epidemiological study suggested that an increase in the nutritional uptake of the natural polyamine spermidine is associated with reduced overall and cancer-specific mortality. Here, we speculate through which mechanisms spermidine might exert such oncopreventive effects. Abbreviations: ACLY, ATP citrate lyase; ATG, autophagy-related gene; CoA, coenzyme A; NSCLC, non-small cell lung cancer.

langue originale	Anglais
Pages (de - à)	362-365
Nombre de pages	4
journal	Autophagy
Volume	15
Numéro de publication	2
Les DOIs	https://doi.org/10.1080/15548627.2018.1539592
état	Publié - 1 févr. 2019

Accès au document

10.1080/15548627.2018.1539592

Autres fichiers et liens

Lien vers la publication dans Scopus

Contient cette citation

@article{a2c6f48057aa4c7cb50bb8cef8f4f343,

title = "Spermidine reduces cancer-related mortality in humans",

abstract = "A recent prospective epidemiological study suggested that an increase in the nutritional uptake of the natural polyamine spermidine is associated with reduced overall and cancer-specific mortality. Here, we speculate through which mechanisms spermidine might exert such oncopreventive effects. Abbreviations: ACLY, ATP citrate lyase; ATG, autophagy-related gene; CoA, coenzyme A; NSCLC, non-small cell lung cancer.",

keywords = "Aspirin, Autophagy, aging, immunosurveillance, inflammation",

author = "Federico Pietrocola and Francesca Castoldi and Oliver Kepp and Didac Carmona-Gutierrez and Frank Madeo and Guido Kroemer",

note = "Publisher Copyright: {\textcopyright} 2018, {\textcopyright} 2018 Informa UK Limited, trading as Taylor & Francis Group.",

year = "2019",

month = feb,

day = "1",

doi = "10.1080/15548627.2018.1539592",

language = "English",

volume = "15",

pages = "362--365",

journal = "Autophagy",

issn = "1554-8627",

number = "2",

}

TY - JOUR

T1 - Spermidine reduces cancer-related mortality in humans

AU - Pietrocola, Federico

AU - Castoldi, Francesca

AU - Kepp, Oliver

AU - Carmona-Gutierrez, Didac

AU - Madeo, Frank

AU - Kroemer, Guido

PY - 2019/2/1

Y1 - 2019/2/1

N2 - A recent prospective epidemiological study suggested that an increase in the nutritional uptake of the natural polyamine spermidine is associated with reduced overall and cancer-specific mortality. Here, we speculate through which mechanisms spermidine might exert such oncopreventive effects. Abbreviations: ACLY, ATP citrate lyase; ATG, autophagy-related gene; CoA, coenzyme A; NSCLC, non-small cell lung cancer.

AB - A recent prospective epidemiological study suggested that an increase in the nutritional uptake of the natural polyamine spermidine is associated with reduced overall and cancer-specific mortality. Here, we speculate through which mechanisms spermidine might exert such oncopreventive effects. Abbreviations: ACLY, ATP citrate lyase; ATG, autophagy-related gene; CoA, coenzyme A; NSCLC, non-small cell lung cancer.

KW - Aspirin

KW - Autophagy

KW - aging

KW - immunosurveillance

KW - inflammation

UR - http://www.scopus.com/inward/record.url?scp=85055711450&partnerID=8YFLogxK

U2 - 10.1080/15548627.2018.1539592

DO - 10.1080/15548627.2018.1539592

M3 - Comment/debate

C2 - 30354939

AN - SCOPUS:85055711450

SN - 1554-8627

VL - 15

SP - 362

EP - 365

JO - Autophagy

JF - Autophagy

IS - 2

ER -