TY - JOUR
T1 - Surgery
T2 - Sterilization reversal: Fertility results
AU - Dubuisson, Jean Bernard
AU - Chapron, Charles
AU - Nos, Claude
AU - Morice, Philippe
AU - Aubriot, Francois Xavier
AU - Garnier, Philippe
PY - 1995/1/1
Y1 - 1995/1/1
N2 - Fertility outcome following sterilization reversal by laparotomy was evaluated. We studied all sterilization reversals performed between January 1978 and December 1991; a total of 226 women were treated. Tubal anastomosis was performed according to the rules for microsurgery. The microsurgical technique comprised two main phases: preparation of the healthy tube segments and the anastomosis carried out on two layers. It was possible to study the subsequent fertility of 206 patients in all, as 20 patients were lost to follow-up (8.8%). Cumulative pregnancy rates were evaluated by life-table analysis. The overall intrauterine pregnancy rate, including births and miscarriages, was 69.9% (144 patients) after 2 years. The cumulative intrauterine pregnancy rate was 62% at 18 months. Analysis of the fertility results demonstrated that age was the most significant predictive factor. The cumulative intrauterine pregnancy rate at 2 years was 83.5% (61 cases) for patients ≤33 years, 70% (35 cases) for patients aged 34-36 years, 62.5% (30 cases) for patients aged 37-39 years, and 51.4% (18 cases) for patients aged ≥ 40 years. Even for patients aged ∼40 years, microsurgical repermeabilization can be retained as the first choice rather than in-vitro fertilization.
AB - Fertility outcome following sterilization reversal by laparotomy was evaluated. We studied all sterilization reversals performed between January 1978 and December 1991; a total of 226 women were treated. Tubal anastomosis was performed according to the rules for microsurgery. The microsurgical technique comprised two main phases: preparation of the healthy tube segments and the anastomosis carried out on two layers. It was possible to study the subsequent fertility of 206 patients in all, as 20 patients were lost to follow-up (8.8%). Cumulative pregnancy rates were evaluated by life-table analysis. The overall intrauterine pregnancy rate, including births and miscarriages, was 69.9% (144 patients) after 2 years. The cumulative intrauterine pregnancy rate was 62% at 18 months. Analysis of the fertility results demonstrated that age was the most significant predictive factor. The cumulative intrauterine pregnancy rate at 2 years was 83.5% (61 cases) for patients ≤33 years, 70% (35 cases) for patients aged 34-36 years, 62.5% (30 cases) for patients aged 37-39 years, and 51.4% (18 cases) for patients aged ≥ 40 years. Even for patients aged ∼40 years, microsurgical repermeabilization can be retained as the first choice rather than in-vitro fertilization.
KW - Sterilization reversal
KW - Tubal anastomosis
KW - Tubal infertility
KW - Tubal microsurgery
UR - http://www.scopus.com/inward/record.url?scp=0029016951&partnerID=8YFLogxK
U2 - 10.1093/oxfordjournals.humrep.a136108
DO - 10.1093/oxfordjournals.humrep.a136108
M3 - Article
C2 - 7657755
AN - SCOPUS:0029016951
SN - 0268-1161
VL - 10
SP - 1145
EP - 1151
JO - Human Reproduction
JF - Human Reproduction
IS - 5
ER -