Symptomatic leptomeningeal metastasis improvement with nivolumab in advanced non-small cell lung cancer patient

Maria Gion; Jordi Remon; Caroline Caramella; Jean Charles Soria; Benjamin Besse

doi:10.1016/j.lungcan.2017.02.022

Symptomatic leptomeningeal metastasis improvement with nivolumab in advanced non-small cell lung cancer patient

Maria Gion, Jordi Remon, Caroline Caramella, Jean Charles Soria, Benjamin Besse

Résultats de recherche: Contribution à un journal › Article › Revue par des pairs

30 Citations (Scopus)

Résumé

Leptomeningeal metastasis (LM) is reported in 3.8% of non-small-cell lung cancer (NSCLC) patients, more frequently in adenocarcinoma, and it correlates with poor prognosis. Data regarding the activity of immune checkpoint inhibitors in LM is lacking. We present a case report about the efficacy of nivolumab in a patient with advanced NSCLC and symptomatic LM.

langue originale	Anglais
Pages (de - à)	72-74
Nombre de pages	3
journal	Lung Cancer
Volume	108
Les DOIs	https://doi.org/10.1016/j.lungcan.2017.02.022
état	Publié - 1 juin 2017

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10.1016/j.lungcan.2017.02.022

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title = "Symptomatic leptomeningeal metastasis improvement with nivolumab in advanced non-small cell lung cancer patient",

abstract = "Leptomeningeal metastasis (LM) is reported in 3.8% of non-small-cell lung cancer (NSCLC) patients, more frequently in adenocarcinoma, and it correlates with poor prognosis. Data regarding the activity of immune checkpoint inhibitors in LM is lacking. We present a case report about the efficacy of nivolumab in a patient with advanced NSCLC and symptomatic LM.",

keywords = "Lung cancer, Meningeal carcinomatosis, Nivolumab",

author = "Maria Gion and Jordi Remon and Caroline Caramella and Soria, {Jean Charles} and Benjamin Besse",

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AU - Gion, Maria

AU - Remon, Jordi

AU - Caramella, Caroline

AU - Soria, Jean Charles

AU - Besse, Benjamin

PY - 2017/6/1

Y1 - 2017/6/1

N2 - Leptomeningeal metastasis (LM) is reported in 3.8% of non-small-cell lung cancer (NSCLC) patients, more frequently in adenocarcinoma, and it correlates with poor prognosis. Data regarding the activity of immune checkpoint inhibitors in LM is lacking. We present a case report about the efficacy of nivolumab in a patient with advanced NSCLC and symptomatic LM.

AB - Leptomeningeal metastasis (LM) is reported in 3.8% of non-small-cell lung cancer (NSCLC) patients, more frequently in adenocarcinoma, and it correlates with poor prognosis. Data regarding the activity of immune checkpoint inhibitors in LM is lacking. We present a case report about the efficacy of nivolumab in a patient with advanced NSCLC and symptomatic LM.

KW - Lung cancer

KW - Meningeal carcinomatosis

KW - Nivolumab

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DO - 10.1016/j.lungcan.2017.02.022

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