Targeting Foxp1 for reinstating anticancer immunosurveillance

Laurence Zitvogel, Guido Kroemer

    Résultats de recherche: Contribution à un journalBrève enquêteRevue par des pairs

    3 Citations (Scopus)

    Résumé

    Transforming growth factor β (TGF-β) is a canonical immunosuppressive cytokine secreted by tumors. In this issue of Immunity, Stephen etal. (2014) reveal that tumor-derived TGF-β deactivates antitumor CD8+ Tcell responses through Tcell upregulation of the FoxP1 transcription factor. Transforming growth factor β (TGF-β) is a canonical immunosuppressive cytokine secreted by tumors. Stephen etal. (2014) reveal that tumor-derived TGF-β deactivates antitumor CD8+ Tcell responses through Tcell upregulation of the FoxP1 transcription factor.

    langue originaleAnglais
    Pages (de - à)345-347
    Nombre de pages3
    journalImmunity
    Volume41
    Numéro de publication3
    Les DOIs
    étatPublié - 18 sept. 2014

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