Targeting Senescence for Next-Generation Cancer Treatments

Eric Gilson; Pierre Soubeyran; Eric Solary

doi:10.1158/2159-8290.CD-24-0089

Targeting Senescence for Next-Generation Cancer Treatments

Eric Gilson, Pierre Soubeyran, Eric Solary

Résultats de recherche: Contribution à un journal › Article › Revue par des pairs

Résumé

Cellular senescence has paradoxical effects on cancer emergence, progression, and therapeutic response. We herein identify four lessons that emerged from studying senescence interaction with cancer and emphasize four bottlenecks in the therapeutic manipulation of cellular senescence to prevent or cure cancer.

langue originale	Anglais
Pages (de - à)	635-638
Nombre de pages	4
journal	Cancer Discovery
Volume	14
Numéro de publication	4
Les DOIs	https://doi.org/10.1158/2159-8290.CD-24-0089
état	Publié - 1 avr. 2024

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10.1158/2159-8290.CD-24-0089

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Contient cette citation

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title = "Targeting Senescence for Next-Generation Cancer Treatments",

abstract = "Cellular senescence has paradoxical effects on cancer emergence, progression, and therapeutic response. We herein identify four lessons that emerged from studying senescence interaction with cancer and emphasize four bottlenecks in the therapeutic manipulation of cellular senescence to prevent or cure cancer.",

author = "Eric Gilson and Pierre Soubeyran and Eric Solary",

note = "Publisher Copyright: {\textcopyright} 2024 American Association for Cancer Research.",

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N2 - Cellular senescence has paradoxical effects on cancer emergence, progression, and therapeutic response. We herein identify four lessons that emerged from studying senescence interaction with cancer and emphasize four bottlenecks in the therapeutic manipulation of cellular senescence to prevent or cure cancer.

AB - Cellular senescence has paradoxical effects on cancer emergence, progression, and therapeutic response. We herein identify four lessons that emerged from studying senescence interaction with cancer and emphasize four bottlenecks in the therapeutic manipulation of cellular senescence to prevent or cure cancer.

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