TET2 loss, a rescue of JAK2V617F HSCs

William Vainchenker; Isabelle Plo

doi:10.1182/blood-2014-10-606624

TET2 loss, a rescue of JAK2V617F HSCs

William Vainchenker, Isabelle Plo

Résultats de recherche: Contribution à un journal › Article 'review' › Revue par des pairs

2 Citations (Scopus)

Résumé

In this issue of Blood, Chen et al¹ and Kameda et al² demonstrate that Tet2 loss has 2 effects in Jak2V617F mice: it increases both the severity of the myeloproliferative disorders and the self-renewal properties of the Jak2V617F hematopoietic stem cells (HSCs).

langue originale	Anglais
Pages (de - à)	212-213
Nombre de pages	2
journal	Blood
Volume	125
Numéro de publication	2
Les DOIs	https://doi.org/10.1182/blood-2014-10-606624
état	Publié - 8 août 2015

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10.1182/blood-2014-10-606624

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title = "TET2 loss, a rescue of JAK2V617F HSCs",

abstract = "In this issue of Blood, Chen et al1 and Kameda et al2 demonstrate that Tet2 loss has 2 effects in Jak2V617F mice: it increases both the severity of the myeloproliferative disorders and the self-renewal properties of the Jak2V617F hematopoietic stem cells (HSCs).",

author = "William Vainchenker and Isabelle Plo",

note = "Publisher Copyright: {\textcopyright} 2015 by The American Society of Hematology.",

year = "2015",

month = aug,

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doi = "10.1182/blood-2014-10-606624",

language = "English",

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journal = "Blood",

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TY - JOUR

T1 - TET2 loss, a rescue of JAK2V617F HSCs

AU - Vainchenker, William

AU - Plo, Isabelle

PY - 2015/8/8

Y1 - 2015/8/8

N2 - In this issue of Blood, Chen et al1 and Kameda et al2 demonstrate that Tet2 loss has 2 effects in Jak2V617F mice: it increases both the severity of the myeloproliferative disorders and the self-renewal properties of the Jak2V617F hematopoietic stem cells (HSCs).

AB - In this issue of Blood, Chen et al1 and Kameda et al2 demonstrate that Tet2 loss has 2 effects in Jak2V617F mice: it increases both the severity of the myeloproliferative disorders and the self-renewal properties of the Jak2V617F hematopoietic stem cells (HSCs).

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U2 - 10.1182/blood-2014-10-606624

DO - 10.1182/blood-2014-10-606624

M3 - Review article

C2 - 25573967

AN - SCOPUS:84920972676

SN - 0006-4971

VL - 125

SP - 212

EP - 213

JO - Blood

JF - Blood

IS - 2

ER -