TY - JOUR
T1 - The host-tumor immune conflict
T2 - From immunosuppression to resistance and destruction
AU - Chouaib, Salem
AU - Asselin-Paturel, Carine
AU - Mami-Chouaib, Fathia
AU - Caignard, Anne
AU - Blay, Jean Yves
PY - 1997/10/1
Y1 - 1997/10/1
N2 - A successful immune response against a tumor is dependent on the cytokine repertoire present at the tumor site. Salem Chouaib and colleagues discuss evidence that, to escape the immune system, tumor cells not only produce immunosuppressive cytokines but also employ strategies involving altered susceptibility to tumor necrosis factor and Fas cytotoxic pathways and, in some circumstances, use of the Fas ligand to neutralize effector cells.
AB - A successful immune response against a tumor is dependent on the cytokine repertoire present at the tumor site. Salem Chouaib and colleagues discuss evidence that, to escape the immune system, tumor cells not only produce immunosuppressive cytokines but also employ strategies involving altered susceptibility to tumor necrosis factor and Fas cytotoxic pathways and, in some circumstances, use of the Fas ligand to neutralize effector cells.
UR - http://www.scopus.com/inward/record.url?scp=0030981706&partnerID=8YFLogxK
U2 - 10.1016/S0167-5699(97)01115-8
DO - 10.1016/S0167-5699(97)01115-8
M3 - Review article
C2 - 9357142
AN - SCOPUS:0030981706
SN - 0167-5699
VL - 18
SP - 493
EP - 497
JO - Immunology Today
JF - Immunology Today
IS - 10
ER -