Résumé
Objective: The purpose of this study was to evaluate the benefit of Oncoplastic Breast Conserving Surgery (BCS) compared to standard BCS after primary CT, in terms of oncologic safety and cosmetic outcomes. Background: The development of new drugs has led to greater use of primary chemotherapy (CT) for bulky breast cancer (BC) and has allowed wider indications for conservative surgery. Patients and methods: We identified 259 patients consecutively treated with BCS for primary BC from January 2002 to November 2010. All patients had undergone Oncoplastic Breast Surgery (OBS) or standard BCS after primary CT. Mastectomy rates, and oncological and cosmetic outcomes were compared. Results: A total of 45 OBS and 214 standard BCS were analyzed. The median tumor size was 40mm in the two groups (p=0.66). The median operative specimen volumes were larger in the OBS group than in the standard group (respectively, 180cm3 and 98cm3, p<0.0001). Re-excision (9% vs 2%) and mastectomy (24% vs 18%) rates were similar (p=0.22 and p=0.30) in the standard BCS group and in the OBS group respectively. At a median follow-up of 46 months, local relapse (p=0.23) and distant relapse (p=0.35) rates were similar. Conclusion: OBS allows excision of larger volumes of residual tumor after primary CT. OBS outcomes results were similar to those of standard BCS.Oncoplastic Breast Conserving Surgery (BCS) after primary chemotherapy allows wider breast resection than standard BCS. Survival and relapse probabilities are similar in both groups.
langue originale | Anglais |
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Pages (de - à) | 1189-1193 |
Nombre de pages | 5 |
journal | Breast |
Volume | 22 |
Numéro de publication | 6 |
Les DOIs | |
état | Publié - 1 janv. 2013 |