Résumé
Identified as a TP53-binding protein, 53BP1 is a key regulator of the cellular response to double-strand breaks, a TP53-independent activity. Recent data have established a new TP53-dependent function for 53BP1 in mitotic surveillance after centrosome loss.
langue originale | Anglais |
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Pages (de - à) | 311-313 |
Nombre de pages | 3 |
journal | Trends in Cell Biology |
Volume | 27 |
Numéro de publication | 5 |
Les DOIs | |
état | Publié - 1 mai 2017 |