TRAITEMENT DES INSULINOMES MALINS METASTATIQUES. DEUX OBSERVATIONS

L. Mounedji-Boudiaf, P. Rougier, S. Culine, T. De Baere, P. Lasser, B. Escudier, M. Ducreux, E. Kaloustian, J. P. Droz, A. Roche

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    Résumé

    Malignant insulinomas are slow growing tumours for which the prognosis is worsened by metastatic disease and sequellae of excess hormone secretion. Management of unresectable tumours includes intravenous chemotherapy and local treatments such as palliative surgery and transcatheter arterial embolization of liver metastases. Long-term survival can also be improved by inhibition of secretory products of the tumour with either octreotide, a somatostatin analogue, or diazoxide. We report two cases of malignant insulinomas with liver metastases for which objective responses were obtained with combination of local treatment and intravenous chemotherapy.

    Titre traduit de la contributionTreatment of metastatic insulinomas. Two case reports
    langue originaleFrançais
    Pages (de - à)894-896
    Nombre de pages3
    journalPresse Medicale
    Volume24
    Numéro de publication19
    étatPublié - 1 janv. 1995

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