TSG101 et cancer du sein: Un gene suppresseur de tumeur bien nomme?

Jean Bénard; Jean Charles Ahomadégbé

TSG101 et cancer du sein: Un gene suppresseur de tumeur bien nomme?

Jean Bénard, Jean Charles Ahomadégbé

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Résumé

In January 1997, PCR genomic analysis of the TSG101 gene showed frequent large intragenic deletions. The investigators used a small cohort of sporadic breast cancers. Li et al. proposed human TSG 101 as a breast tumor supressor gene. Since then, several teams have worked on large series of breast cancers, using a variety of techniques. They have shown that intragenic deletion, if it exists at all, is rare. Is TSG101 a tumor gene or an impostor?.

Titre traduit de la contribution	Breast cancer: Is TSG101 a well named gene?
langue originale	Français
Pages (de - à)	1141-1142
Nombre de pages	2
journal	Bulletin du Cancer
Volume	84
Numéro de publication	12
état	Publié - 1 déc. 1997

mots-clés

Breast cancer
TSG101 gene

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title = "TSG101 et cancer du sein: Un gene suppresseur de tumeur bien nomme?",

abstract = "In January 1997, PCR genomic analysis of the TSG101 gene showed frequent large intragenic deletions. The investigators used a small cohort of sporadic breast cancers. Li et al. proposed human TSG 101 as a breast tumor supressor gene. Since then, several teams have worked on large series of breast cancers, using a variety of techniques. They have shown that intragenic deletion, if it exists at all, is rare. Is TSG101 a tumor gene or an impostor?.",

keywords = "Breast cancer, TSG101 gene",

author = "Jean B{\'e}nard and Ahomad{\'e}gb{\'e}, {Jean Charles}",

year = "1997",

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AU - Ahomadégbé, Jean Charles

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N2 - In January 1997, PCR genomic analysis of the TSG101 gene showed frequent large intragenic deletions. The investigators used a small cohort of sporadic breast cancers. Li et al. proposed human TSG 101 as a breast tumor supressor gene. Since then, several teams have worked on large series of breast cancers, using a variety of techniques. They have shown that intragenic deletion, if it exists at all, is rare. Is TSG101 a tumor gene or an impostor?.

AB - In January 1997, PCR genomic analysis of the TSG101 gene showed frequent large intragenic deletions. The investigators used a small cohort of sporadic breast cancers. Li et al. proposed human TSG 101 as a breast tumor supressor gene. Since then, several teams have worked on large series of breast cancers, using a variety of techniques. They have shown that intragenic deletion, if it exists at all, is rare. Is TSG101 a tumor gene or an impostor?.

KW - Breast cancer

KW - TSG101 gene

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M3 - Article 'review'

C2 - 9587367

AN - SCOPUS:0031417156

SN - 0007-4551

VL - 84

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JO - Bulletin du Cancer

JF - Bulletin du Cancer

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