Tubulin-targeting agent combination therapies: Dosing schedule could matter

Eric Solary

    Résultats de recherche: Contribution à un journalArticle 'review'Revue par des pairs

    4 Citations (Scopus)

    Résumé

    Tubulin-binding agents are potent cytotoxic drugs that are largely used to treat haematological malignancies and solid tumours. In this issue of British Journal of Pharmacology, doxorubicin was shown to decrease the activity of vincristine when administered simultaneously, unless cell cycle arrest mechanisms were disrupted. This observation emphasizes the need to better explore schedule-dependent antagonist effects in anticancer drug combination therapies.

    langue originaleAnglais
    Pages (de - à)1555-1557
    Nombre de pages3
    journalBritish Journal of Pharmacology
    Volume168
    Numéro de publication7
    Les DOIs
    étatPublié - 1 avr. 2013

    Contient cette citation