Résumé
Tubulin-binding agents are potent cytotoxic drugs that are largely used to treat haematological malignancies and solid tumours. In this issue of British Journal of Pharmacology, doxorubicin was shown to decrease the activity of vincristine when administered simultaneously, unless cell cycle arrest mechanisms were disrupted. This observation emphasizes the need to better explore schedule-dependent antagonist effects in anticancer drug combination therapies.
langue originale | Anglais |
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Pages (de - à) | 1555-1557 |
Nombre de pages | 3 |
journal | British Journal of Pharmacology |
Volume | 168 |
Numéro de publication | 7 |
Les DOIs | |
état | Publié - 1 avr. 2013 |