Undifferentiated Carcinoma of Nasopharyngeal Type of Tonsil

Jerzy Klijanienko, Christian Micheau, Nacer Azli, Esteban Cvitkovic, François Eschwege, Patrick Marandas, Jean Pierre Armand, Odile Casiraghi, Guy Schwaab, Florent Vathaire

    Résultats de recherche: Contribution à un journalArticleRevue par des pairs

    31 Citations (Scopus)

    Résumé

    A review of 2262 squamous cell carcinomas of the tonsillar region seen at the Institut Gustave-Roussy, Villejuif, France, from 1970 to 1986 showed 1837 well- and poorly differentiated squamous cell carcinomas and 425 undifferentiated squamous cell carcinomas. Eighteen patients with undifferentiated squamous cell carcinomas presented histologic characteristics of undifferentiated carcinomas of nasopharyngeal type. Radiosensibility and radiocurability (complete sterilization with 70 Gy administered) was found in this group with an excellent long-term control of local disease (77% at 10 years actuarial). Epstein-Barr virus–related serologic tests were performed for seven patients. Four of them presented the serologic anti–Epstein-Barr virus titer patterns, generally associated with undifferentiated carcinomas of nasopharyngeal type (1280 to 5120 for viral capsid antigen/IgG and 40 to 320 for viral capsid antigen/ IgA). These observations confirm that undifferentiated carcinomas of the nasopharyngeal type may arise outside the nasopharynx.

    langue originaleAnglais
    Pages (de - à)731-734
    Nombre de pages4
    journalArchives of Otolaryngology--Head and Neck Surgery
    Volume115
    Numéro de publication6
    Les DOIs
    étatPublié - 1 janv. 1989

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