Wound healing delay after central venous access following DCF/VEGF-trap therapy

Charles Ferté; Christophe Massard; Christian Moldovan; Eric Desruennes; Yohann Loriot; Jean Charles Soria

doi:10.1007/s10637-009-9227-7

Wound healing delay after central venous access following DCF/VEGF-trap therapy

Charles Ferté, Christophe Massard, Christian Moldovan, Eric Desruennes, Yohann Loriot, Jean Charles Soria

Résultats de recherche: Contribution à un journal › Article › Revue par des pairs

3 Citations (Scopus)

Résumé

Summary: Hypertension, proteinuria, thromboembolic or bleeding events are well-recognized complications occurring while targeting VEGF pathway. Wound healing dysfunctions have also been described in patients undergoing major surgery. For the first time, we report wound healing delay after central venous access following DCF-VEGF-Trap. VEGF-Trap may affect both angiogenesis and reepithelialization which are necessary to the normal repair process.

langue originale	Anglais
Pages (de - à)	583-585
Nombre de pages	3
journal	Investigational New Drugs
Volume	27
Numéro de publication	6
Les DOIs	https://doi.org/10.1007/s10637-009-9227-7
état	Publié - 1 déc. 2009

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10.1007/s10637-009-9227-7

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title = "Wound healing delay after central venous access following DCF/VEGF-trap therapy",

abstract = "Summary: Hypertension, proteinuria, thromboembolic or bleeding events are well-recognized complications occurring while targeting VEGF pathway. Wound healing dysfunctions have also been described in patients undergoing major surgery. For the first time, we report wound healing delay after central venous access following DCF-VEGF-Trap. VEGF-Trap may affect both angiogenesis and reepithelialization which are necessary to the normal repair process.",

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AU - Ferté, Charles

AU - Massard, Christophe

AU - Moldovan, Christian

AU - Desruennes, Eric

AU - Loriot, Yohann

AU - Soria, Jean Charles

PY - 2009/12/1

Y1 - 2009/12/1

N2 - Summary: Hypertension, proteinuria, thromboembolic or bleeding events are well-recognized complications occurring while targeting VEGF pathway. Wound healing dysfunctions have also been described in patients undergoing major surgery. For the first time, we report wound healing delay after central venous access following DCF-VEGF-Trap. VEGF-Trap may affect both angiogenesis and reepithelialization which are necessary to the normal repair process.

AB - Summary: Hypertension, proteinuria, thromboembolic or bleeding events are well-recognized complications occurring while targeting VEGF pathway. Wound healing dysfunctions have also been described in patients undergoing major surgery. For the first time, we report wound healing delay after central venous access following DCF-VEGF-Trap. VEGF-Trap may affect both angiogenesis and reepithelialization which are necessary to the normal repair process.

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KW - VEGF-Trap

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